![]() ![]() Nevertheless, in order to achieve maximal protection against stroke and to minimize bleeding complications, warfarin therapy must be tightly controlled and maintained within a narrow therapeutic range of international normalized ratio (INR) values between 2 and 3. Warfarin is contraindicated in pregnancy, as it passes through the placental barrier and may cause bleeding in the fetus leading to spontaneous abortion, stillbirth, neonatal death, and preterm birth 9. Warfarin is a conventional oral anticoagulant, commonly used to treat blood clots such as deep vein thrombosis and pulmonary embolism, and to prevent stroke in people who have atrial fibrillation, valvular heart disease or artificial heart valves 8. Subsequently, long term treatment is oral vitamin k antagonist (VKA) warfarin for 3–12 months 5–7. Recommended treatment of CVT is anticoagulation unless contraindicated, initially with intravenous unfractionated heparin (UFH) or low molecular weight heparin (LMWH) i.e. Risk factors of CVT are different from that of ischemic stroke, with pregnant or postpartum women having 3.5 times higher risk of developing CVT than non-pregnant or postpartum women of similar age 3, 4. It occurs three times more frequently in women, especially during pregnancy and with use of hormonal contraceptives, reaching up to 12 cases per one million deliveries 2. Annual occurrence is estimated to be 3–4 cases per one million. ![]() Cerebral venous thrombosis (CVT) is a rare cause of stroke in the general population, accounting for about 0.5–1% of all strokes 1. ![]()
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